This article examines the application of artificial intelligence (AI) technologies to improve human-computer interaction (HCI) and foster cooperation in graphic design. Comprehensive study and practical use reveal that AI integration significantly enhances HCI's effectiveness and precision while introducing unique collaborative models in graphic design. The research employs natural language processing (NLP) and deep learning technologies in HCI to provide natural dialogue and intelligent responses between humans and machines by developing intelligent question-answering systems and automated task-processing capabilities. Data research indicates that with the implementation of AI, user-computer interface efficiency has increased by 21%, and the mistake rate has decreased by 12%. This accomplishment substantially enhances user experience and facilitates computers in comprehending and addressing user requirements more effectively. The biocompatibility and comfort of users of these substances are of concern. Investigating novel flexible biosensors is imperative to enhance these devices' adaptability, comfort, and interaction. In visual design, the research employs AI's picture recognition and analysis skills to facilitate intelligent recommendations and automatic modifications of design aspects. AI can autonomously produce visual components that align with the designer's goal and approach by analyzing several design scenarios using machine learning algorithms. Data analysis indicates that the design effectiveness of AI-assisted design projects has increased by 30%, and the caliber of the outputs has substantially enhanced.